A Rare Look Inside Your Biology, with Enveda
What your blood can tell you about your health, mapped through metabolomics at Edge Esmeralda.
We are bringing deep metabolomic profiling to Edge Esmeralda. Participants will be able to contribute to real research and receive a private personal profile.
Remember to buy tickets to Edge Esmeralda (30 May - June 27), in Healdsburg, CA.
TLDR
Enveda is running a week-long metabolomics experiment for Edge Esmeralda residents during Vital Futures week, June 1 to June 8, 2026.
15 to 20 participants will receive free mass spec profiling of hundreds of circulating metabolites across multiple blood draws, plus an optional add-on that captures how your metabolism responds to cold plunge and sauna.
You walk away with a personal metabolomic profile and a de-identified comparison against the rest of the cohort. This is the kind of deep phenotyping usually locked behind clinical or research settings.
Sign-up is open to confirmed Edge Esmeralda ticket holders.
At Edge City, our popup villages function as living labs. Residents run experiments on sleep, longevity protocols, consciousness, governance, and more. The thing that sets a village apart from a conference is that 500+ people live on a roughly shared schedule for weeks at a time, which makes it possible to study biology in ways that are hard to replicate anywhere else.
We’re excited to announce a partnership with Enveda to run a metabolomics experiment during Week 1 of Edge Esmeralda 2026, led by Pablo Lubroth and his team. The study sits inside Vital Futures, our anchor health track, alongside Alethios, wearable data collection, and a Women’s Health Summit.
Why this matters
Your metabolome is the full set of small molecules circulating in your blood at any given moment. It reflects how you process food, regulate energy, fight off disease, and respond to stress in real time. Most people never see it. The infrastructure to measure it sits inside labs and clinical trials, and a single read rarely tells you much on its own. What you really want is a sequence of reads across different states, so you can see what stays stable and what moves.
That is what this study is designed to capture. Repeated draws on days 1, 2, and 7 of the week, paired with standardized meals and careful logging of sleep, caffeine, and exercise. For residents who also want to participate, paired pre- and post-exposure draws around cold plunge or sauna sessions, so Enveda can characterize acute perturbation and recovery in the same individuals.
What you get as a participant
Participants will receive their metabolomic profile along with interpretation of what those metabolites do, and a de-identified view of how their profile compares to the rest of the cohort. If you also opt into Alethios studies or are wearing a ring or watch throughout the residency, those datasets layer on top of each other. Combined, that is one of the more complete pictures of your biology you can get anywhere, for free.
How it works, in plain English
The study runs over seven days:
Days 1 and 2: one fasting draw in the morning, plus non-fasting draws before lunch and dinner. Meals are standardized, and breakfast and lunch will be provided on both days for participants.
Day 7: one fasting morning draw.
Optional cold plunge / sauna: if you’re going to the plunge or sauna anyway, pair it with a scheduled draw. Pre-draw immediately before, post-draw 15 minutes after you exit. Enveda records temperature and duration.
Draws are done on-site at Edge Esmeralda by trained nurses. Samples are centrifuged, frozen, and shipped on dry ice to Enveda HQ for mass spec analysis. Logistics and fees are covered by Enveda.
The bigger picture
This is part of a broader layer of experiments running across Edge Esmeralda this year. Alethios is giving every resident access to their platform to design and run structured studies. Christine Kyrula is capturing wearable time series data across the residency, a continuous read of physiology across a large co-located population. Vital Futures brings in Bay Area coaches, practitioners, and founders for daily hands-on sessions.
Any one of these experiments is interesting. Put them in the same place at the same time, across the same people, and you get something you cannot replicate with a lab or a conference. We care a lot about making this stack work well, because it is what turns “I tried this and felt better” into data worth publishing.
Who this is for
Enveda is looking for 15 to 20 participants who are:
Ages 18 to 65
In generally good health with a BMI between 18.5 and 29.9
Able to comply with fasting requirements and attend scheduled draws across the week
Willing to log meals, sleep, and exercise across the study window
There are exclusions around pregnancy, active illness, and specific chronic conditions. Full eligibility criteria live in the study protocol and will be sent to participants during screening.
How to sign up
Sign-up for the Enveda metabolomics study is open to confirmed Edge Esmeralda ticket holders. If you do not yet have a ticket, apply to Edge Esmeralda 2026 at edgeesmeralda.com.
Edge Esmeralda 2026 runs May 30 to June 27 in Healdsburg, California. The Enveda study runs June 1 to June 8.
Questions? Reach out to info@edgecity.live.
Enveda is a biotech company using mass spectrometry-based metabolomics and AI to discover and develop medicines from nature. Their research platform maps the chemistry of plants and the human metabolome at scale.
Edge City creates popup villages around the world that convene people working at the frontiers of tech, science, and society. Our mission is to act as a society incubator: a living lab to experiment with new ideas, technologies, cultures, and organizations, with the goal of advancing human flourishing.